PM ET game airing live on Amazon Prime Video, bookmakers have posted player props for Isaac Guerendo. NFC West rivals play in ...

Most starters were on the sideline late in Week 14's lopsided win, while only one D-lineman played over 30 snaps.

The top injuries to monitor. Plus, Jake Ciely's player rankings, weather reports and more fantasy and betting insights.

Neither will be eliminated from playoff contention with a loss, but it would be devastating for their 2024 playoff chances.

Getting hurt the Sunday before a Thursday night game gave San Francisco 49ers fans plenty of reason to be skeptical about ...

Isaac Guerendo was initially uncertain for Thursday night, but the rookie looks like he might give it a go. Here's the latest ...

The San Francisco 49ers running back is questionable with a sprained foot, but per ESPN’s Adam Schefter: he “plans to play” ...

The 49ers won’t be down to their 4th-string running back tonight against the Rams as Isaac Guerendo is expected to play ...

The San Francisco 49ers have been decimated by injuries all year, specifically at the running back position. Christian ...

The Los Angeles Rams will take on the San Francisco 49ers in Week 15 of the NFL season on Thursday. This prediction is based ...

Isaac Guerendo became the team's starter last week and the rookie scored two touchdowns against the Bears, but his day ended ...

The San Francisco 49ers running back spot has been a position of focus for fantasy football players throughout the season, ...